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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed52e959fe7271bd2113d123a4492ffe09c1361514963269e56016666611a56b' 
  AND token = 'BFdRqkr2ilaRVh5tyKKVv81Yk6n12gCShGkBmYtUjUo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}