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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22ab68ce14a4983f0c46a47a57d6957e01dd378ca5f51de19f6d5d0128d81885' 
  AND token = '8YNsfJwvjesdyDqsClngIBrD/Dr8qbD1r8kJwxpU4Tw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}