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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eb0c5df5b1fba9151ff2b8a7660844f325bd55820e4d82a38f784450c0493513' 
  AND token = '3KYpIRApLa/x6v8MiCQq3491UP5qFDpXaAV2fA9pZW8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}