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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f80052b79156f2cb8c682bb120b28706e291cea922f80001be3ae6409701e32' 
  AND token = '28ESV91qWXJ205w2lst3W+LURA5ZhlrVlAWgkmN9NBg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00061

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}