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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f19a8facf82361a583a13eacc14cd6d8607718445c1b7a6071b17245bce466f' 
  AND token = 'MqdqxEBUEH1Ra5b0Wgrjxng36+w//0kndNP0Lt06z3Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}