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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0a5bc6b73e1d7a2dd541ce6f6e2c8e9e7919720960361db3c108391ef2cc7f1' 
  AND token = 'wNWcicWO1O41fmMvZm0ZKeOV/lY2UDbUxwyw+aXeYF0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}