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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e6218f1ef5639bb4b19fa6fa514e4dae49bf29baf274c9d9ca276e8997d16fc' 
  AND token = 'Bt1DamGiBgNhDde5lrxJQQ9xs3Kgx4Y00aBNwLHXD4k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}