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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b323e9b81fd8c9e5691db70bf023b16c29fd25edf171ad324995f2220dba9c2' 
  AND token = 'atct8VQxdvMfFzShfD91AUcAXF+2aSWLEhC79CqNtug=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}