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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51b3d2129bf5a367866448152c07572bc0cb6faca131a0170afe3ea17690e224' 
  AND token = 'YWLVq2XMcv+K2MOSqwZeB2ayv0Rgoa1z3gpItUCNJH0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}