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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb22a75225bed5b5f4b3698e0b7da7e172bb2d314155b319c9b817a44f07473b' 
  AND token = 'ZiiI8aRLdjOw4TltjrytDG9dZLF2dEnqhafhI9Qzh3g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}