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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0820c7ff67568c51ef54edd9b07107a071644538c339eefd422bf046cd463b7' 
  AND token = 'YyR21ABJFdC+e6asKtZvc9tD4soYbjYjuVdauJ1a1p0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}