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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a8ade9c8145fedf9ea71f2f4864934a90f873f0b6c5c887577c52c9043260ac' 
  AND token = 'RqdgSmrDI0axHM4OLwXfpYkX566AjNHZk68mDB7/IbY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}