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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb914342b1a53db8be85a15c17d4e183f05a887d59ac8b6c5435c1f885d670eb' 
  AND token = 'chVJf9Sp9lLXSiFqy9lQO6M9HHOOB2PuRdiKpE+vmBE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}