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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '186219f0d4a779033e06511196a21fdf73a4b1759cf057af33fc419a19a60937' 
  AND token = 'Rv4FVMGtI3SCBVl3mj2nI4jnIPWXlnHFq2OLiItxOEc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}