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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8875933ecea2fa2e2f5e8fa4f212454632857eff852643af80efc1f6eb7442fb' 
  AND token = 'EHt1rc462i9HCRTW0PGHVqVaVifNjZssN73NqeY+0cI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}