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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a27bfce40b8c24ed30da370a6228280134c4e4c134ce2ef78501eeee014e6078' 
  AND token = 'XaaPZieRXmIgbWWz4aAfxhaB5tmtnDLd9lUCvJ7/6f0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}