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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ece6257e89c1c197ab16237ae99c1720937959e11011878c3f1bcd4362df272' 
  AND token = 'fqhPe5Ts8i8mmpX4ZAg2398NgBCeOrm96eb9ujMIY1Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}