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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3466a1f0bd7f2f2983e5b631aa79a19d663fd90a4a8099c90b41984831a059b9' 
  AND token = 'Qq0SRkhcAZILwf+wZcDyWqBdwoHcWe+Hfjba1+wy57I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}