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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f97722e08b69a800fd2b8998d385c78592ef8815cb0fce8f1742783417918e77' 
  AND token = 'LBxYvUj2Z5xLRihqMvb+Eii0X2CAK01Ia5Q1sFLveeg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}