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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a6ed8c0d80fa001e7c8b516d0cc0bde6fea3910eb0c93cdf7cd753119f022981' 
  AND token = 'Pcl87YB66hMAtvpOXBO0YMuL26f8g7OOQnhOQho7cho=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}