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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca99d415f42b008cd9e20efcfff76d9d840e284495075bdde41e62411000e1ab' 
  AND token = '18u2Fj1y2kRSAcxxFdbcNm+F6JzDD3zKd5Y/2EbFVPg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}