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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cdab0427dd78cf7a37e92298b9332bbddf966e9bb870d4c6cefe3fd8fd92790f' 
  AND token = 'iUi9E7HqRSmlwUEgEwp/8xVc/AGk+ofdRpWd8LZptrM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}