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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c05e3e552c850c5bb539377bed524fb2a121d0d80d85768e2df5527d21ab64b' 
  AND token = 'JVIbPtszqiY4QPLsIlo4+Y9J0EowJaTttb0knQgMJQk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}