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SELECT 
  1 
FROM 
  cscart_ec_print_temp_designs 
WHERE 
  session_id = '4GAX-8ENK-87TV-7NKC-X7CH-1E23-MDA6-X2RA' 
  AND product_id = 160 
  AND expires_at > 1770181847 
  AND confirmed = 'Y' 
LIMIT 
  1

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}