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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b0b79a4f644c4370d274d5d4a7ac603bb99d5afcaf446c77ac2e208cd99d429' 
  AND token = 'bBafhoDUIKgT3PunhecuN9DO8eXVMbyS1jFRByk0tU4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}