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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4edf106c7cd79bea56cef36b075130876675675c80c9a01646ba22de4a6a1051' 
  AND token = 'Dxc7MSD0pMt7ddy2iOuM1Yl5spmoMnEv6tOSTT06MyY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}