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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52f3d9594fb01dbe7643a4235b97ca693750ac208a560e0ca4d2d53b8f3e82b0' 
  AND token = 'NRzkkc+cbGufvEuoEy2HY7+icOxsVog7Tegt+Q3Cbj0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}