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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8eb51452d3911e5a66709f6f95df4ee9f45364255b51928b967101d6c3dcc49' 
  AND token = 'beOiMbRzW70VkeummJ550FjGFlUn1yG1LzexbHs67ik=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}