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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f9b4518240271d708b19ad477d3f6b02499eaecdc845931381a4d0739ce96056' 
  AND token = 'H+LYmAlX7A9oH0bQ6DOLlZHwGWdNwk6tObKv7gUuSr0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}