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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '601198fbf3c0104ec12ae014ebed191035473325a5644d4d240c0cc37643af6b' 
  AND token = 'JRSh13QJBQv3cSQ3yFpSQL6/eFA3k+/qKZ6b/k0Npjc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}