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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed593d732479445933cebf18a48aae7d12338a704b91f23de2f78757b1516129' 
  AND token = 'nci2t5gtVdJJsitR/XBb6K9UOm3VmR+WGn8nyEcLOf8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}