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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5b7d2bf60d39d58ea55e3e050860f22186a27f70d2547cde9d45fc49d7a6d21' 
  AND token = '6N8+dE75UdJE1e+6NK0OPGJrtrA1rHqIwq0Q7qBRQvs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}