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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1021fd443c47186b7704f9424553786076575cda08b3e3dd247e1911edcf7b7' 
  AND token = 'eEWA95WIQLDN7U8niTobgnonL+G3wmQjMKpA/9n59mY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}