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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dfb618fdf93ef6f4664d012be715d74acda1b8654d2cb71ffbc87e6c1d394e65' 
  AND token = 'Mt8Vfb3Vmv5gGuMILcZdx3bcKz5A0ZMiHrXSdUfHGOQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}