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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80fcb08b60c379a2dd7f34e099691da966b4caa30cb3807e9db51ef145604107' 
  AND token = '4+Ae2ZmeSOg7dDaQpH3jTVFitbpGIBvCJPee00v92pE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}