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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4bafc95da69c6be72859dd6ab7d1e545e993db403a4276c555c88467bc88241' 
  AND token = '9WC7Egx0yO1hRrgs+ULVTeyjunD5pqs0EVMbE8wMsdk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}