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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '721fab0bc8938aea37977f49f3806e56ce13dea155aeda9ed6a7ac309b7fba6d' 
  AND token = '0s/ypydjSSSf0awMXAn5CSgz/1Jzg9TJRiOOGakC6l4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}