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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '76dd157f06f801b8160fa37c8143a0a9c5123c973060ad8b6751e99d758e3808' 
  AND token = '62pRyllLuy/a9baUUUbqjTNYki756mvT6cBiXToptnQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}