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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12b10426cb40b6df81e02f0e5ba8ae70b3a3f64119f1b953839562a87e41de61' 
  AND token = 'Zv/62Op3rz0x+Zc68C0pDU7I+9QK5gsBeWmFHD0b/rY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}