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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27e23a5e64949daceb3849aa6f4eaadeb22ee08cdfb7faeacf10333d14b43638' 
  AND token = 'WZzFcF3vfSUb7xffyRp1nIUU1WzNT203tE8crhPkARA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}