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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b1d3961c5f0529154d4223f053e37ea2d8cee1f182e0391595e558ad6922a01' 
  AND token = 'FhgE4dS4X/B7s47SnBvMxU9mTM7xtZPyQDC1Fl8YKp4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}