Sandbox

SELECT 
  1 
FROM 
  cscart_ec_print_temp_designs 
WHERE 
  session_id = '5WX9-NEYN-9E4Q-Z3LL-HEE3-XHUL-2YOY-I6A9' 
  AND product_id = 100 
  AND expires_at > 1770181216 
  AND confirmed = 'Y' 
LIMIT 
  1

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}