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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f88861f7a1b0a2cb73a871eead3ee626dc4659f9dd4dc272605c122fa32496a' 
  AND token = 'pSlnMPhIp6p/6AX/SYguoss1N1GdCP5UjmDKRiO5mNQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}