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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65904f27199d37500db2186d9121abd88577d27ca5f1329c6152847af8d9e8f5' 
  AND token = 'NZXvx0OTwpLjXeU7pxNZ2FCoid3uV7e8Yox0kT3epmI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}