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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0002729b7521aacce5633f47ce27b3e9c73f312e0aea42bb45398a222f20ca69' 
  AND token = '1T3NDVOZSG74ayGHZU9vM4MBJ/hM5nw2XhuE7Udpj1k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}