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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '34082aaa4e6feff77f2e9622c7bd3414dfd91af8b6caf4d8f3c796da162bf720' 
  AND token = '7XIOGa9yHlhb+on5flt6D6DIWUMxC/1xBq8vnxBbABM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}