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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd46a55280cb3332266f47af47b1dd3f4e82be408d2fc1034a7ef428afcb9dd7a' 
  AND token = 'HqofU0se1/hYzTPntTTsXERU4j8OD8zQYlYzxBAcFXo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}