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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45219c3ba2c6d6a13714400029fafb492bcae5221c1a903d13dc7ac9d114c767' 
  AND token = 'Xa6I/RuM/2AVthl1PRK5dh1Lota+e5MDDqPryn3tt6g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}