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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd11fcc6092ea7271056ecbd640d355b3bafdbec6279412ec7b6114afdfcc9116' 
  AND token = 'N1Qf4g8lZLcRzEalzOCkjOt99sGhJFG6JdFSdkJd+Mk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}