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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d3d9474420aab56fe9c30e60a8e40f0b421677056d911869a9cd0a4ac7b8606' 
  AND token = 'Nq+MGwoCc1v4ZgdtNvGMq2JzcXeTnHrTJ2+GNfbbAs0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}